NCT03221998

The Effect of Timing of Intravenous Paracetamol Administration on Post-surgical Pain

The Effect of Timing of Intravenous Paracetamol Administration on Post-surgical Pain and Cytokines Levels Following Laparoscopic Sleeve Gastrectomy

• Status: Unknown
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 126 (estimated)
• Sponsor: Soroka University Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 100 Years
• Healthy volunteers: Accepted

Summary

This study is designed as a population-based prospective randomized cohort study. A prospective cohort of patients admitted to laparoscopic sleeve gastrectomy due to morbid obesity

Detailed description

All adult consecutive patients admitted to surgical departments for laparoscopic sleeve gastrectomy will be enrolled prospectively. For the purposes of the current study we want to determine how much paracetamol (acetaminophen) can reduce the cytokines levels in these patients The study enrollment period is planned to be a year. The follow-up period for each patient will be until discharge from the hospital.

Conditions

• Obesity, Morbid

Interventions

Type	Name	Description
DRUG	IV paracetamol	100 gram paracetamol infusion for moderate pain management
DRUG	IV saline (NaCl 0.9 %)	100 ml of Normal Saline (IV NaCl 0.9 %) as placebo

Timeline

• Start date: 2017-07-01
• Primary completion: 2019-03-01
• Completion: 2020-03-01
• First posted: 2017-07-19
• Last updated: 2017-07-25