Trials / Unknown

UnknownNCT03220750

University Hospital Advanced Age Pregnant Cohort

Status: Unknown
Phase: —
Study type: Observational
Enrollment: 22,000 (estimated)

Sponsor: Peking University · Academic / Other
Sex: Female
Age: 35 Years – 60 Years
Healthy volunteers: Accepted

Summary

The University Hospital Advanced Age Pregnant (UNIHOPE) Cohort is the major part of the National Key Research and Development Program on Reproductive Health \& Major Birth Defects Control and Prevention Project, which is funded by the Ministry of Science and Technology of China. The Project is led by Prof. Zhao Yangyu, from the Department of Gynecology \& Obstetrics, Peking University Third Hospital, and the UNIHOPE cohort is led by Prof. Jian-meng Liu, the Co-PI of the Project.

Detailed description

The UNIHOPE Cohort is set up to provide comprehensive evidence for the prevention and treatment of gestational complications in pregnant women with advanced maternal age, and therefore, to meet the growing clinical challenges of increasing pregnant women with advanced age in the two-child era. The UNIHOPE Cohort is planning to recruit 22,000 pregnant women aged ≥35 years from 9 large obstetrical center of major University-affiliated Hospitals across China, between July 2016 and December 2020. All women will be enrolled prior to 14 wks of gestation, followed up at 24-28 wks, 32-34 wks of gestation, delivery, and 42 days postpartum. Data including demographics, medical history, reproductive history, prenatal health care, gestational complications, and pregnancy and birth outcomes will be collected via electronic data capture system. Venous blood of the pregnant women will be collected at enrollment and each follow-up visit during pregnancy, and placental tissue, cord blood and hair of the newborn will also be collected.

Conditions

Timeline

Start date: 2017-03-28
Primary completion: 2020-12-31
Completion: 2020-12-31
First posted: 2017-07-18
Last updated: 2017-07-18

Locations

9 sites across 1 country: China

Source: ClinicalTrials.gov record NCT03220750. Inclusion in this directory is not an endorsement.