NCT03219567

Whole Eye Optical Coherence Tomography (OCT) to Improve Refractive Surgery and Eye Care

• Status: Terminated
• Phase: —
• Study type: Interventional
• Enrollment: 82 (actual)
• Sponsor: Duke University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

The overall objective is to develop the hardware systems and software algorithms necessary to make accurate measurements of the whole eye with optical coherence tomography (OCT). The research procedure that each subject will undergo is imaging with the OCT system. Three populations will be included: 1. Normals to ensure the imaging range of the system, 2. Patients with previous LASIK who will be undergoing cataract surgery, and 3. Patients with a history of cataract surgery or high myopia. The third group will also undergo MRI imaging for comparison. There are no known risks to the subject from imaging with optical coherence tomography beyond what is normal for standard ocular photographic procedures. Light exposure is below ANSI limits. In groups 2 and 3, clinical parameters drawn from the OCT images will be compared to standard of care imaging.

Conditions

• Image, Body

Interventions

Type	Name	Description
DEVICE	Optical Coherence Tomography (OCT)	Optical coherence tomography (OCT) is a non-contact, micrometer scale imaging technique, it provides clinicians and researchers with high resolution in vivo images sufficient to visualize layered microanatomy in 3D. The study team will develop the hardware systems and software algorithms necessary to enable simultaneous OCT imaging of all the refractive surfaces of the eye.
DEVICE	Magnetic resonance imaging (MRI)	Magnetic resonance imaging (MRI) is a medical imaging technique that uses a magnetic field and computer-generated radio waves to create detailed images of the organs and tissues in the body.

Timeline

• Start date: 2014-10-09
• Primary completion: 2019-11-21
• Completion: 2019-11-21
• First posted: 2017-07-17
• Last updated: 2022-04-04
• Results posted: 2022-04-04

Locations

1 site across 1 country: United States