NCT03217474

Femtosecond Laser-assisted Corneal Debridement for Herpes Simplex Keratitis

A Randomized Controlled Clinical Trial of Corneal Debridement for the Treatment of Herpes Simplex Epithelial Keratitis

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Chunxiao Wang · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

The purpose of the study is to learn if adding femtosecond laser-assisted corneal debridement to a standard therapy of oral ganciclovir can help shorten the healing time of herpes simplex epithelial keratitis (HSK).

Conditions

• Herpes Simplex Keratitis

Interventions

Type	Name	Description
PROCEDURE	FLDEB	The eye will be anesthetized, and femtosecond laser technology will be used to remove epithelial tissue (diameter: 8mm; depth: 100micron) that includes the loosened diseased corneal epithelial cells. Antibiotic ointments and drops will be instilled postoperatively.
DRUG	Ganciclovir (GCV)	Patient will be treated with GCV orally (200mg, 3 times a day, for 14 days).
DEVICE	Femtosecond laser	A commercial femtosecond laser to create a particular shaped graft for transplantation.

Timeline

• Start date: 2017-07-20
• Primary completion: 2018-12-30
• Completion: 2019-12-30
• First posted: 2017-07-14
• Last updated: 2018-02-22

Locations

1 site across 1 country: China