Clinical Trials Directory

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UnknownNCT03216447

A Study of Patient Adherence and Convenience to Immunosuppressive Agents in Newly Liver Transplant

A Prospective, Multi-center, Open-labeled, Randomized Clinical Trial of Patient Adherence and Convenience to Immunosuppressive Agents in Newly Liver Transplant Recipients to Compare QD Early Conversion and BID Tacrolimus Formulation.

Status
Unknown
Phase
Phase 4
Study type
Interventional
Enrollment
150 (estimated)
Sponsor
Chang Gung Memorial Hospital · Academic / Other
Sex
All
Age
18 Years – 70 Years
Healthy volunteers
Not accepted

Summary

A study of patient adherence and convenience to immunosuppressive agents in newly liver transplant recipients - a prospective, multi-center, open-labeled, randomized clinical trial for comparison between once-daily early conversion and twice-daily tacrolimus formulation.

Detailed description

This is prospective, multi-center, open-labeled, randomized study to investigate adherence of administration of once-daily tacrolimus formulation (Advagraf®) in newly Taiwanese (Chinese) liver transplant patients. The procedure of liver transplantation will follow the site-specific procedure. Each subject will be randomized on postoperative day 15 (POD15; defined Day 14 +/- 1)

Conditions

Interventions

TypeNameDescription
DRUGAdvagrafTacrolimus prolonged-release hard capsules (QD)
DRUGPrografTacolimus capsules (q12h)

Timeline

Start date
2017-11-23
Primary completion
2023-08-31
Completion
2025-09-30
First posted
2017-07-13
Last updated
2020-06-05

Locations

1 site across 1 country: Taiwan

Source: ClinicalTrials.gov record NCT03216447. Inclusion in this directory is not an endorsement.