Trials / Completed
CompletedNCT03216265
A Proof of Concept Clinical Study to Investigate the Effects of an Experimental Cosmetic Moisturiser on the Barrier Function of Human Skin on the Face and Forearm
A Proof of Concept (POC) Clinical Study to Investigate the Effects of a Developmental Cosmetic Moisturising Cream on the Barrier Function of Human Skin on the Face and Forearm
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 69 (actual)
- Sponsor
- GlaxoSmithKline · Industry
- Sex
- Female
- Age
- 18 Years – 65 Years
- Healthy volunteers
- Accepted
Summary
The objective of this POC clinical study is to investigate the impact of the test product (Developmental Cosmetic Moisturising Cream) on skin barrier function and skin moisturisation on the forearm and face after 4 weeks of twice daily application compared to no treatment in participants with dry sensitive skin.
Detailed description
Areas on the volar forearm and each side of the face, will be selected for measurements of transepidermal water loss (TEWL) and corneometry to be conducted . A physical challenge and a regression period of 5 days is also included to evaluate skin barrier function and moisturisation. A regression period of 5 days (Days 30, 31, 32, 33 and 34) of no study product use following the 4 week treatment phase is also included to evaluate skin barrier function and moisturisation.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Test product (Moisturising cream) | Participants will be instructed to apply their assigned product to the randomly assigned sites twice daily (in the morning and evening). |
| OTHER | Positive control (Commercial market place moisturising cream) | Participants will be instructed to apply their assigned product to the randomly assigned sites twice daily (in the morning and evening). |
| OTHER | No treatment | No treatment. |
Timeline
- Start date
- 2017-02-23
- Primary completion
- 2017-04-19
- Completion
- 2017-04-24
- First posted
- 2017-07-13
- Last updated
- 2019-04-18
- Results posted
- 2019-04-18
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT03216265. Inclusion in this directory is not an endorsement.