NCT03215732

Cross Sectional Survey on the Burden and Impacts of Chronic Hepatitis B in the Rural Area of Niakhar, Senegal

Cross Sectional Survey on the Burden and Impacts of Chronic Hepatitis B Virus Infection in the Rural Area of Niakhar, Senegal

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 3,119 (actual)
• Sponsor: ANRS, Emerging Infectious Diseases · Other Government
• Sex: All
• Age: 6 Months
• Healthy volunteers: Accepted

Summary

This study aims at estimating the prevalence of chronic hepatitis B virus (HBV) infection in rural Senegal (area of Niakhar) and at evaluating the associated burden in terms of both health-related and socio-economic consequences.

Detailed description

The prevalence of chronic HBV infection in Senegal is among the highest worldwide (10% to 17%) but available prevalence estimates relie on studies conducted in specific subgroups (such as military, pregnant women or blood donors). The prevalence of HBV chronic infection remains undocumented in the general population of Senegal, and its health-related and socio-economic consequences need to be estimated. This research is based on a cross-sectional survey conducted in the general population with collection of biological, socio-behavioral and economic data at two levels (at the participants' home and in healthcare centers) in the area of Niakhar (located at 135 kms at the East of Dakar). The research includes three phases as follows: (i) Preliminary phase: information and communication about the research within the community, training of stakeholders and pilot survey (ii) Collection of data in the general population (iii) Communication of results on HBV status to participants and collection of additional data among HBV chronic individuals

Conditions

• Chronic Hepatitis b

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	HBV testing with dried blood spots (DBS) technique	Survey participants will be tested at home for chronic HBV infection using the DBS technique (collection of drops of whole blood dried onto filter paper).

Timeline

• Start date: 2017-10-19
• Primary completion: 2019-07-31
• Completion: 2019-07-31
• First posted: 2017-07-12
• Last updated: 2019-09-09

Locations

1 site across 1 country: Senegal