NCT03215420

Comparison of 3 Methods to Diagnose Endolymphatic Hydrops in Meniere's Disease

Diagnostic Agreement of Electrophysiological Audiovestibular Examinations With Magnetic Resonance Imaging (MRI) of the Inner Ear in Revealing Endolymphatic Hydrops (EH) in Patients With Certain or Probable Meniere's Disease (MD)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 41 (actual)
• Sponsor: Centre Hospitalier Universitaire Dijon · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is to compare 3 methods for the diagnosis of endolymphatic hydrops (EH) in patients with Meniere's disease: MRI 3 Tesla (to visualise EH directly), and functional explorations, namely electrocochleography and dephasing of acoustic distortion products (which are modified by the EH). The research hypothesis is that the examinations will show agreement in the diagnosis of EH, and that the results obtained (quantitative values) will vary in the same direction over time and during flares of MD.

Conditions

• Endolymphatic Hydrops

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	MRI 3T

Timeline

• Start date: 2016-09-08
• Primary completion: 2018-07-03
• Completion: 2018-10-03
• First posted: 2017-07-12
• Last updated: 2024-02-22

Locations

1 site across 1 country: France