NCT03215290

Trans-parenchymal Compressing Suture in Major Liver Resection

Application of Trans-parenchymal Compressing Suture in Major Liver Resection to Decrease Cutting Surface Related Complication.

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 382 (actual)
• Sponsor: Tongji Hospital · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Non-anatomical liver resection with appropriate resection margin was regarded as a potential curative treatment for selected major hepatic carcinoma due to preserving maximal normal liver, especially in cirrhotic patients. But occurrence of cutting surface related complications become a main challenge.

Detailed description

In order to better manage the cutting surface after liver resection, we further applied trans-parenchymal compressing suture to "not good" cutting surface in hope of decreasing cutting surface related complication. A majority of studies investigating cutting surface management are limited to non-surgical treatments, such as the application of hemostasis agents including fibrin sealants, oxidized cellulose, and absorbable gelatin sponge13-15 . But there is no consensus regarding the necessity of the hemostatic agent application to the liver cutting surface. Up to date, few studies investigate surgical suture management of the cutting surface in liver resection.

Conditions

• Liver Carcinoma Resectable

Interventions

Type	Name	Description
PROCEDURE	TCS	The cutting surface recognized as "not good" cutting surface was further trans-parenchymal compressing sutured, if possible, using a hepatic needle.

Timeline

• Start date: 2016-10-01
• Primary completion: 2017-01-01
• Completion: 2017-02-01
• First posted: 2017-07-12
• Last updated: 2017-07-12