NCT03214341

Assessment of Mediastinal Masses With Diffusion Weighted MR Imaging

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 24 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Differentiation between benign and malignant mediastinal tumors as well as characterization and grading of malignancy which is essential for treatment planning as well as for prognosis

Detailed description

Differentiation between benign and malignant mediastinal tumors as well as characterization and grading of malignancy is essential for treatment planning as well as for prognosis . MRI presents valuable diagnostic information in assessing the mediastinum. In addition, special applications have been developed over recent years diffusion-weighted magnetic resonance imaging is one such technique The advent of echo-planar imaging technique has rendered diffusion weighted imaging of the abdomen and thoracic cavity possible . Quantitative assessment of the mediastinal mass is possible by calculation of apparent diffusion co-efficient value ,which is related to the proportion of extracellular and intracellular component. The apparent diffusion co-efficient is inversely correlated with tissue cellularity. It is lower in viable tumor tissue with densely packed diffusion-hindering obstacles than in tissue with less densely packed obstacles such as tumor necrosis and benign tissue .

Conditions

• Mediastinal Tumor

Interventions

Type	Name	Description
RADIATION	MRI diffusion	using MRI diffusion to differentiate between benign and malignant mediastinal masses

Timeline

• Start date: 2017-12-01
• Primary completion: 2019-12-01
• Completion: 2019-12-30
• First posted: 2017-07-11
• Last updated: 2017-07-11

Locations

1 site across 1 country: Egypt