NCT03212144

The Anti-Inflammatory Effects of Exercise and Peanut Consumption

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 3 (actual)
• Sponsor: New York State Psychiatric Institute · Academic / Other
• Sex: All
• Age: 21 Years – 45 Years
• Healthy volunteers: Accepted

Summary

This study will enroll and randomly assign 30 sedentary, healthy overweight men and women to two groups. Participants will either start by consuming peanuts for 4 weeks, and then go on to exercise at high intensity intervals (HIIT) for 4 weeks, or the reverse order. The study will test and compare the effect of peanuts and exercise on inflammation and heart rate variability as indicators of heart health. Specifically, the study will measure inflammation in the blood because there is evidence that higher inflammation is found in heart disease patients. There is also evidence that inflammation is related to death as a result of heart disease in healthy individuals. Finally, there are ongoing trials targeting these markers to improve heart health. The study hypothesizes that peanuts and exercise will reduce inflammation. It is also expected to find less inflammation because exercise and peanut consumption activate a part of the nervous system that has been shown to cause a similar effect. Additionally, previous studies show that inflammation involves the mitochondria in the cell, the part of the cell that produces energy. For this reason, it is expected that exercise and peanuts will cause changes in the mitochondria. The study will test and compare mitochondrial activity in response to peanut consumption and exercise.

Conditions

• Peanut Consumption
• High Intensity Aerobic Exercise

Interventions

Type	Name	Description
OTHER	High Intensity Interval Training	Subjects will exercise according the the high intensity aerobic interval training regiment four times a week for four weeks
OTHER	Peanut Consumption	Subjects will consume peanuts twice a day to replace 20% of their daily caloric intake for four weeks.

Timeline

• Start date: 2017-08-20
• Primary completion: 2018-12-31
• Completion: 2019-12-31
• First posted: 2017-07-11
• Last updated: 2020-04-06
• Results posted: 2020-04-06

Locations

1 site across 1 country: United States