NCT03211728

Does Perioperative Pregabalin Reduce Postoperative Pain After Arthroscopic Anterior Cruciate Ligament Reconstruction Surgery Under Spinal Anesthesia?

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 96 (actual)
• Sponsor: Yonsei University · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

The investigators hypothesize that perioperative oral administration of pregabalin would reduce postoperative pain and produce reduction in postoperative opioid consumption after anterior cruciate ligament (ACL) reconstruction . Patients are randomly assign to 1 of 2 groups. The placebo group receive placebo capsules 1 hour before surgery and 12 hours after initial dose. The pregabalin group receive pregabalin 150 mg, respectively at the same points.

Conditions

• Anterior Cruciate Ligament (ACL) Reconstruction

Interventions

Type	Name	Description
DRUG	pregabalin	The intervention group receive pregabalin 150 mg 1 hour before surgery and 12 hours after initial dose.
DRUG	placebo	The placebo group receive placebo 150 mg 1 hour before surgery and 12 hours after initial dose.

Timeline

• Start date: 2017-07-19
• Primary completion: 2019-02-08
• Completion: 2019-02-08
• First posted: 2017-07-07
• Last updated: 2019-02-20

Locations

1 site across 1 country: South Korea