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UnknownNCT03211572

The EMPOwER Study Evaluating Multiparameter Gene Testing as a Predictor of Short Term Endocrine Therapy Response in Hormone Receptor Positive Breast Cancers

Evaluating Multiparameter Gene Testing as a Predictor of Short Term Endocrine Therapy Response in Hormone Receptor Positive Breast Cancers: The EMPOwER Study

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
82 (estimated)
Sponsor
Ottawa Hospital Research Institute · Academic / Other
Sex
Female
Age
18 Years
Healthy volunteers
Not accepted

Summary

Evaluating Multiparameter Gene Testing as a Predictor of Short Term Endocrine Therapy Response in Hormone Receptor Positive Breast Cancers

Detailed description

The clinical trial will be a prospective, two strata, non-blinded, single institution, Health Canada approved, Window of Opportunity trial with 2 weeks of pre-surgical endocrine therapy using either anastrozole or tamoxifen. Tissue from the initial biopsy and from surgery will be sent for Ki67 analysis using the NanoString® Assay.

Conditions

Interventions

TypeNameDescription
DRUGTamoxifenParticipants will take endocrine therapy for 2 weeks prior to surgery.

Timeline

Start date
2017-08-01
Primary completion
2018-08-01
Completion
2018-08-01
First posted
2017-07-07
Last updated
2017-07-07

Source: ClinicalTrials.gov record NCT03211572. Inclusion in this directory is not an endorsement.

The EMPOwER Study Evaluating Multiparameter Gene Testing as a Predictor of Short Term Endocrine Therapy Response in Horm (NCT03211572) · Clinical Trials Directory