NCT03211507

Idiopathic Pulmonary Fibrosis Job Exposures Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 960 (actual)
• Sponsor: Imperial College London · Academic / Other
• Sex: Male
• Age: —
• Healthy volunteers: Not accepted

Summary

A case-control study to investigate whether job exposures are an under-recognized cause of idiopathic pulmonary fibrosis (IPF) using an interview to collect information about previous jobs and a blood test to investigate genetic susceptibility.

Detailed description

Idiopathic pulmonary fibrosis (IPF) is a scarring lung disease. It damages the air sacs that allow oxygen to be transferred into the blood and transported to vital organs. These changes make people with IPF cough and feel short of breath. It not known what causes the damage. People who get IPF are usually older than 40; it's a very serious illness that cannot be cured and gets worse over time. Statistics show that IPF is becoming more common in the UK but it's not known why. It can be difficult for doctors to tell if someone has IPF or another disease called asbestosis.

Conditions

• IPF
• Idiopathic Pulmonary Fibrosis

Interventions

Type	Name	Description
OTHER	Computer-assisted telephone interview	Occupational history
GENETIC	Genetic analysis	To include analysis of known susceptibility markers

Timeline

• Start date: 2017-05-01
• Primary completion: 2019-10-05
• Completion: 2019-10-05
• First posted: 2017-07-07
• Last updated: 2019-12-12

Locations

1 site across 1 country: United Kingdom