Trials / Completed
CompletedNCT03211338
Inflammation and Cell Maturation in Preterm Delivery Placentas - in Vitro and in Vivo Effect of Progesterone
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 115 (actual)
- Sponsor
- Hillel Yaffe Medical Center · Other Government
- Sex
- Female
- Age
- 18 Years – 40 Years
- Healthy volunteers
- Accepted
Summary
The aim of this study is to investigate the In Vitro and In Vivo effect of progesterone on immature myeloid cells (IMC), inflammation characteristics and maturation into dendritic cells (DC).
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | Culture with progesterone | Progesterone, a steroid hormone will be cultured with placental IMC cells or peripheral blood CD14+ monocyte cells |
| BIOLOGICAL | Culture without progesterone | Culture of placental IMC cells or peripheral blood CD14+ monocyte cells without progesterone |
| BIOLOGICAL | Culture with growth factors | Culture of placental IMC cells with growth hormones only and analysis |
Timeline
- Start date
- 2017-07-15
- Primary completion
- 2022-06-06
- Completion
- 2022-06-06
- First posted
- 2017-07-07
- Last updated
- 2022-06-23
Locations
1 site across 1 country: Israel
Source: ClinicalTrials.gov record NCT03211338. Inclusion in this directory is not an endorsement.