NCT03211260

Effects of Proprioceptive Focal Stimulation (EQUISTASI) on Freezing of Gait in Parkinson's Disease

Effects of Proprioceptive Focal Stimulation (EQUISTASI) on Freezing of Gait in Parkinson's Disease: a Open, Single-arm Trial

• Status: Terminated
• Phase: N/A
• Study type: Interventional
• Enrollment: 42 (actual)
• Sponsor: ASST Gaetano Pini-CTO · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Freezing of gait (FOG) is a common disabling condition in Parkinson's disease (PD), causes falls, and impairs quality of life. Therapeutic options for this symptom are limited and of limited efficacy. Besides, the pathophysiology has been not clarified yet. Proprioceptive sensitivity is likely to play a role and recent studies have reported that high-frequency microfocal vibratory stimulation exert a modulatory effect of proprioceptive reflex circuits and could be considered a valuable treatment strategy. However, evidence is not available. The present study was designed to collect preliminary evidence of efficacy of a vibrotactile device (Equistasi) for the treatment of FOG.

Conditions

• Freezing of Gait
• Parkinson Disease

Interventions

Type	Name	Description
DEVICE	EQUISTASI	Equistasi is a nanotechnology for proprioceptive focal stimulation. Every patient will receive four patches to be placed on both legs for 4 weeks.

Timeline

• Start date: 2017-12-11
• Primary completion: 2019-07-19
• Completion: 2019-07-19
• First posted: 2017-07-07
• Last updated: 2019-09-12

Locations

1 site across 1 country: Italy