Trials / Completed
CompletedNCT03210584
Multimodal Evaluation of Cartilage Lesions of Patellofemoral Joint
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 10 (actual)
- Sponsor
- University Hospital, Grenoble · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Evaluation and comparison of histological analysis, 9,4 tesla MRI, Full-Field Optical Coherence Tomography (FFOCT) and ultrasound-based navigation system for cartilage degeneration analysis of patellofemoral joint.
Detailed description
Knee osteoarthritis (OA) is a common and debilitating chronic degenerative disease of the articular cartilage. Despite recent progress in the field of cartilage imaging, no routinely used clinical imaging modality has the ability to evaluate and monitor changes in cartilage degeneration. This observationnal, pilot, prospective, non randomized, uncontrolled, monocentric study aim to compare three of the most innovative imaging systems, namely the 9,4 Tesla MRI, the FFOCT (Full-Field Optical Coherence Tomography) and the ultrasound-based navigation system in order to image healthly to severely degraded human cartilage samples. All methods will be cross-correlated and compared with histological data considered as the gold standard.
Conditions
Timeline
- Start date
- 2016-10-01
- Primary completion
- 2017-01-01
- Completion
- 2018-09-01
- First posted
- 2017-07-07
- Last updated
- 2018-09-11
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT03210584. Inclusion in this directory is not an endorsement.