NCT03206489

Nasal High Frequency Oscillation for Respiratory Distress Syndrome in Twins Infants

Nasal High Frequency Oscillation for Respiratory Distress Syndrome in Preterm Twins Infants

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 200 (estimated)
• Sponsor: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University · Academic / Other
• Sex: All
• Age: 30 Minutes – 6 Hours
• Healthy volunteers: Not accepted

Summary

The investigators compared advantages and disadvantages of two forms of noninvasive respiratory support -noninvasive high-frequency oscillatory ventilation (nHFOV) or nasal continuous positive airway pressure (nCPAP) -as a primary mode of ventilation in preterm twins infants with respiratory distress syndrome

Detailed description

Invasive ventilation is related to development of adverse pulmonary and nonpulmonary outcomes in ventilated infants. Various modes of noninvasive respiratory support are being increasingly used to minimize the incidence of bronchopulmonary dysplasia (BPD). The aim of this trial to compare the effects of noninvasive high frequency oscillatory ventilation (NHFOV) and nasal continuous positive airway pressure (NCPAP) in preterm twins infants as the primary mode.

Conditions

• Nasal High Frequency Oscillation Ventilation

Interventions

Type	Name	Description
DEVICE	noninvasive high-frequency ventilation (nHFOV)	noninvasive high-frequency ventilation (nHFOV) as a primary mode of ventilation in one of the preterm twins infants with respiratory distress syndrome
DEVICE	nasal continuous positive airway pressure (nCPAP)	nasal continuous positive airway pressure (nCPAP) as a primary mode of ventilation in another of the preterm twins infants with respiratory distress syndrome

Timeline

• Start date: 2017-08-01
• Primary completion: 2024-06-30
• Completion: 2024-06-30
• First posted: 2017-07-02
• Last updated: 2022-10-25

Locations

1 site across 1 country: China