NCT03198091

Efficacy of Dun Ye Guan Xin Ning Tablet in Patients With Stable Angina Pectoris

An Open Label, Single Arm, Multiple Center Study Observing the Efficacy of Dun Ye Guan Xin Ning Tablet in Patients With Coronary Artery Disease of Angina Pectoris

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 1,000 (estimated)
• Sponsor: Peking University First Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This registry is designed to investigate factors affecting the efficacy of Dun Ye Guan Xin Ning tablet on patients with stable angina. The potential hypothesis is that Dun Ye Guan Xin Ning has a better effect on different subgroup patients with certain characteristics.

Detailed description

A total of 1000 eligible patients enrolled from 20 centers will take standard medications of care for stable angina plus Dun Ye Guan Xin Ning tablet for 6 months. Symptoms, questionnaires (SAQ, PSQI, and angina pectoris quantitative table of Chinese medicine symptoms scale), lipid, fasting glucose, homocysteine, EKG, blood pressure and other physical examination will be collected at baseline and follow-up. Among them, 200 patients will measure and inflammation biomarkers and endothelial function for further evaluation.

Conditions

• Coronary Heart Disease

Interventions

Type	Name	Description
DRUG	Dun Ye Guan Xin Ning	Dun Ye Guan Xin Ning tablet 320 mg orally every time and 3 times per day for 6 months.

Timeline

• Start date: 2017-03-30
• Primary completion: 2018-06-01
• Completion: 2018-12-31
• First posted: 2017-06-23
• Last updated: 2017-06-23

Locations

1 site across 1 country: China