NCT03195309

A Comparison of Different Concentration Ropivacaine for Patient-controlled Epidural Analgesia

A Comparison of Different Concentration Ropivacaine Combination With Fentanyl for Patient-controlled Epidural Analgesia After Cesarean Delivery

• Status: Unknown
• Phase: Phase 1 / Phase 2
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: Kaohsiung Medical University Chung-Ho Memorial Hospital · Academic / Other
• Sex: Female
• Age: 20 Years – 45 Years
• Healthy volunteers: Not accepted

Summary

To compare the postoperative analgesic effect and the intensity of motor block in different concentration ropivacaine plus fentanyl when used epidurally with a patient-controlled analgesia device after Cesarean delivery.

Detailed description

1. Written informed consent must be obtained before any study specific procedures are undertaken. 2. All patients were received epidural anesthesia with 2% Lidocaine and patient-controlled epidural analgesia (PCEA) for post- operative pain control. PCEA randomly allocated into three groups. Group A patients received 0.08% ropivacaine plus 4 mcg /mL fentanyl, Group B patients received 0.08% ropivacaine plus 2mcg /mL fentanyl, and Group C patients received 0.16 % ropivacaine plus 2 mcg /mL fentanyl. Dermographic data, dosage of PCEA during first 48 hours post-operation，NRS scores, patient satisfaction and the intensity of motor block will be recorded and analyzed.

Conditions

• Epidural Anesthesia
• Cesarean Section

Interventions

Type	Name	Description
DRUG	Ropivacaine	Compare different concentration of ropivacaine and fentanyl for elective Cesarean delivery post operative pain control.
DRUG	Fentanyl	Compare different concentration of ropivacaine and fentanyl for elective Cesarean delivery post operative pain control.

Timeline

• Start date: 2017-01-20
• Primary completion: 2018-12-01
• Completion: 2019-06-01
• First posted: 2017-06-22
• Last updated: 2017-06-22

Locations

1 site across 1 country: Taiwan