NCT03195062

Fructose Extra-splanchnic Metabolism and Its Effects on Systemic Flux of Substrates (FruPP)

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 9 (actual)
• Sponsor: University of Lausanne · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

In parallel to the dramatic rise in metabolic diseases and diabetes observed over the past fifty years, the generalization of added sugar in processed food led to a marked increase in fructose consumption in almost all countries, and epidemiological studies demonstrated that the consumption of sugar-sweetened beverage (containing at least 50% of fructose) is associated with the development of diabetes, hepatic steatosis, dyslipidemia and obesity. The objective of the study is to measure the amount of fructose that escape first-pass hepatic extraction after oral ingestion (fructose+glucose), and gain insights into its metabolic fates with the use of tracers.

Conditions

• Test Meal

Interventions

Type	Name	Description
OTHER	Test meal	Liquid test meal (fructose+glucose)

Timeline

• Start date: 2017-03-23
• Primary completion: 2018-06-30
• Completion: 2018-08-31
• First posted: 2017-06-22
• Last updated: 2018-10-18

Locations

1 site across 1 country: Switzerland