NCT03193879

Effects of Particulate Matter on the Pulmonary Function and Acute Exacerbation of COPD and Asthma

Effects of Particulate Matter on the Lung Function and Acute Exacerbation of COPD and Asthma Patients--A Multi-center Cohort Study

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 505 (actual)
• Sponsor: Peking Union Medical College Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Accepted

Summary

Particulate matter(PM) exposure has been shown to increase the morbidity and mobility of a variety of respiratory diseases, including COPD and asthma. This study focus on the effects of PM on the pulmonary function and acute exacerbation of COPD and asthma patients in China, where PM exposure is much heavier than the United States and European countries.

Detailed description

Particulate matter(PM) exposure has been shown to increase the morbidity and mobility of a variety of respiratory diseases, including COPD and asthma. This study focus on the effects of PM on the pulmonary function and acute exacerbation of COPD and asthma patients in China, where PM exposure is much heavier than the United States and European countries. This study is an observational study which lasts 3 years. Primary outcome measures:Change in spirometry (FEV1) of COPD, asthma patients and healthy volunteers in response to different exposure doses of PM.

Conditions

• Pulmonary Function

Timeline

• Start date: 2015-12-01
• Primary completion: 2021-09-01
• Completion: 2021-09-01
• First posted: 2017-06-21
• Last updated: 2021-09-21

Locations

1 site across 1 country: China