Clinical Trials Directory

Trials / Terminated

TerminatedNCT03191526

A Study of KW-0761 in Subjects With HTLV-1 Associated Myelopathy (HAM)

A Phase 3 Multicenter, Randomized, Double-Blind and Placebo-Controlled Study, and Open Study of KW-0761 in Patients With HTLV-1 Associated Myelopathy (HAM)

Status
Terminated
Phase
Phase 3
Study type
Interventional
Enrollment
66 (actual)
Sponsor
Kyowa Kirin Co., Ltd. · Industry
Sex
All
Age
20 Years
Healthy volunteers
Not accepted

Summary

The objective of this study is to assess the efficacy and safety of KW-0761 after intravenous injections in subjects with HTLV-1 associated myelopathy (HAM) in Japan.

Detailed description

The effects of KW-0761 (0.3 mg/kg) on the Osame's motor disability score (OMDS) of subjects with HTLV-1 associated myelopathy (HAM).

Conditions

Interventions

TypeNameDescription
DRUGKW-0761 0.3 mg/kg IVIntravenous injection every 12 weeks.
DRUGPlacebo (saline)Intravenous injection every 12 weeks.

Timeline

Start date
2017-05-22
Primary completion
2019-06-06
Completion
2021-08-31
First posted
2017-06-19
Last updated
2022-04-14

Locations

16 sites across 1 country: Japan

Source: ClinicalTrials.gov record NCT03191526. Inclusion in this directory is not an endorsement.