NCT03190486

Perception of Baby's Painful Cry in fMRI

Perception of Baby's Painful Cry: Investigation in fMRI to Neuronal Activity Related to Empathy in Adults

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (actual)
• Sponsor: Centre Hospitalier Universitaire de Saint Etienne · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

Crying is the primary signaling strategy available to the human newborn for eliciting parental care. Yet, the investigators only have superficial understanding of the information carried by cries, and how this information is perceived by parents. Using modern tools of sound processing and functional Magnetic Resonance Imaging (fMRI) experiment, this study aims to investigate cry-induced brain activation in adult depending on the cry's acoustic properties expressing various degrees of stress and distress levels. For that, Adults will be tested inside a fMRI magnet to determine their brain activations elicited by different babies cries according to whether the cry was evoked in a pain situation or not. The cerebral activity will be investigated in relation to acoustic features of cries (e.g. with pitch and/or roughness variations). To test if the gender or parentally of adult listeners influence their perceptions and brain responses, the task will be applied to 2 different groups (men and women not-parents). The hypothesis is that the brain of adult listeners will be able to discriminate adequately the intensity of the pain mediated by the cries. This process should involve brain areas such as the insular and the orbito frontal cortex that are known to participate in the integration of pain intensity and pain controls. The experiment should also determine which one of the acoustic features is able to transmit pain and to recruit brain areas involved in pain processes.

Conditions

• Magnetic Resonance Imaging
• Neuronal Activity

Interventions

Type	Name	Description
OTHER	functional Magnetic Resonance Imaging (fMRI)	During fMRI, healthy volunteers will listen 80 baby's cry.

Timeline

• Start date: 2017-07-24
• Primary completion: 2018-07-05
• Completion: 2018-07-05
• First posted: 2017-06-16
• Last updated: 2018-10-10

Locations

1 site across 1 country: France