NCT03190109

Bone Age Determined by Ultrasound (BAUS) in Brazilian Control Children

Analyses of Bone Age Determined by Ultrasound in a Cohort of Brazilian Control Children and Adolescents: Comparison With Conventional Bone Age Determined by X-Ray

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 500 (estimated)
• Sponsor: Faculdade de Ciências Médicas da Santa Casa de São Paulo · Academic / Other
• Sex: All
• Age: 6 Years – 16 Years
• Healthy volunteers: Accepted

Summary

Aiming to validate the use of bone age determined by ultrasound (BAUS) in Brazilian children, normal control students will be studied. X-Ray bone age (RXBA) and BAUS will be determined in 500 children and adolescents of both genders, with chronological age varying from 6-16 years. Concordance analysis and the correlation between both BA determination methods will be performed.

Detailed description

Bone age is a valuable method to recognize the maturation status of development and growth. Classical analyses is performed by using the Greulich and Pyle X-Ray measurement. Such analyses have some restrictions such as intra- and inter observer variability, and variable synchronicity of bone maturation. Bone age determined by ultrasound (BAUS) has been indicated as a fast and reproducible method, allowing decimal BA determination and avoiding the need for X-Ray. Our aim is to validate the BAUS method in Brazilian normal controls. School students of both genders, with age varying from 6 to 16 years will be included.

Conditions

• Control, Population

Timeline

• Start date: 2016-10-13
• Primary completion: 2017-09-01
• Completion: 2018-03-01
• First posted: 2017-06-16
• Last updated: 2017-06-16

Locations

1 site across 1 country: Brazil