NCT03189082

Microbotox for Lower Face Rejuvenation

"Microbotox" Versus Intramuscular Botulinum Toxin in Lower Face Rejuvenation: A Crossover Clinical Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 15 (actual)
• Sponsor: St Joseph University, Beirut, Lebanon · Academic / Other
• Sex: Female
• Age: 18 Years – 90 Years
• Healthy volunteers: Accepted

Summary

The purpose of this study is to evaluate the efficiency of the intradermal injection of botulinum toxin in lower face rejuvenation. The study will also compare this intervention with the "Nefertiti Lift" intramuscular injection technique.

Detailed description

The abobotulinumtoxinA will be used for the intervention. The abobotulinumtoxinA will be prepared by adding 2.5 cc of normal saline to a 500-unit Dysport© (Ipsen Ltd, Berks, UK) vial. Further dilution to the appropriate Microbotox concentration will be done in the syringe itself. Each 1mL syringe of Microbotox solution will contain 20-28 units of onabotulinumtoxinA per mL of solution. Preinjection frontal, oblique and lateral patient pictures will be taken (at rest and with contraction) Injection points: A series of 100-150 intradermal microdroplets injection points 1 cm apart will be delivered in the lower face. The area to be injected is bounded by a line 3 fingerbreadths above and parallel to the lower border of the mandible, 1 fingerbreadth posterior to the depressor anguli oris, and all the way down over the cervicomental angle and anterior neck to the upper border of the clavicle, and posteriorly to the anterior border of the sternocleidomastoid. In the average patient, 2 syringes of 28 units per mL of microbotox will be used to cover the entire area. In heavier necks, 3 syringes of 28 units per mL will be used. In thinner necks, 2 syringes of 20 units per mL will be used. Follow up will be done at 15 days for post injection pictures. A total of 15 patients will be recruited

Conditions

• Botulinum Toxin
• Rejuvenation
• Therapy
• Neck

Interventions

Type	Name	Description
PROCEDURE	Microbotox	Microbotox is the injection of multiple microdroplets of diluted botulinum toxin into the dermis of the lower face

Timeline

• Start date: 2017-08-10
• Primary completion: 2017-09-10
• Completion: 2017-10-04
• First posted: 2017-06-16
• Last updated: 2017-10-06

Locations

1 site across 1 country: Lebanon