NCT03188926

Surgical Treatment of Long Bone Metastases

Surgical Treatment for Long Bone Metastases With Intramedullary Nail or Endoprosthetic Reconstruction

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 120 (actual)
• Sponsor: Istituto Ortopedico Rizzoli · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: —

Summary

To provide treatment guidelines for patients with long bone metastatic disease based on observational study and to propose an algorithm to guide orthopedic surgeons in decision-making for these patient.

Detailed description

The objectives of this study were to examine clinical outcomes after reconstruction with intramedullary fixation (IMN) or endoprosthetic reconstruction (EPR) with a specific focus on (1) the rate of complication or failure; (2) differences in complication rates by anatomic site; (3) functional results as assessed by the Musculoskeletal Tumor Society System (MSTS); (4) differences in complication rate between patients treated with INM versus EPR; and (5) differences in survival in patients with metastatic bone disease based on disease-specific, laboratory, and demographic information.

Conditions

• Bone Metastases
• Surgery

Interventions

Type	Name	Description
PROCEDURE	intramedullary fixation or endoprosthetic reconstruction	Surgical treatment of impending or pathologic fracture in the extremities

Timeline

• Start date: 2016-01-04
• Primary completion: 2017-12-31
• Completion: 2020-01-31
• First posted: 2017-06-16
• Last updated: 2020-08-04

Locations

1 site across 1 country: Italy