Trials / Unknown
UnknownNCT03183258
Vascularised Sentinel Skin Flaps to Detect Rejection in Pancreas Transplantation
- Status
- Unknown
- Phase
- Phase 1 / Phase 2
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- Sponsor
- University of Oxford · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
This pilot study aims to validate the use of vascularised donor-derived sentinel skin flaps for diagnosing rejection in pancreas transplantation. The aim of the study is to investigate the use of sentinel skin flaps in clinical practice and assess whether rejection occurs concordantly or discordantly between the skin flap and the transplanted abdominal organs. If successful, sentinel skin may allow improved immune surveillance and thereby facilitate earlier treatment of rejection with subsequent improvements in allograft survival and patient morbidity.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Sentinel skin flap | Donor-derived vascularised composite allograft (sentinel skin flap) |
Timeline
- Start date
- 2016-05-19
- Primary completion
- 2019-10-01
- Completion
- 2020-10-01
- First posted
- 2017-06-12
- Last updated
- 2019-04-17
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT03183258. Inclusion in this directory is not an endorsement.