NCT03181425

Magnetic Resonance Imaging Diffusion Tensor Tractography for Early Osteoarthritis Assessment

Evaluation of Magnetic Resonance Imaging Diffusion Tensor and Knee Cartilage Tractography Reconstructions for the Study of Early Osteoarthritis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 8 (actual)
• Sponsor: University Hospital, Grenoble · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The aim of this study is the evaluation of new MRI tractography maps for early knee osteoarthritis assessment.

Detailed description

Knee osteoarthritis (OA) is a common and chronic degenerative disease of the articular cartilage. Despite recent progress in the field of cartilage imaging, no routinely used clinical imaging modality has the ability to evaluate and monitor changes in cartilage degeneration. More and more studies report the benefits of Magnetic Resonance (MR) diffusion tensor imaging (DTI) in the study of early knee osteoarthritis and in particular the new MRI contrasts generating the Track Weighted Imaging (TWI) technique. This observationnal, pilot, prospective, unrandomized and uncontrolled study aim to evaluate, for the first time, the new MRI tractography maps for the assessment of early knee osteoarthritis. This study doesn't modify the medical care of the patient.

Conditions

• Knee Osteoarthritis

Timeline

• Start date: 2016-10-01
• Primary completion: 2017-04-01
• Completion: 2017-06-01
• First posted: 2017-06-08
• Last updated: 2017-07-06

Locations

1 site across 1 country: France