NCT03177109

Comparison of Different Desensitizers in Reducing Dentinal Hypersensitivity

Comparison of Fluoride Varnish With Two Different Desensitizers in Reducing Dentinal Hypersensitivity

• Status: Unknown
• Phase: Phase 3
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Aga Khan University · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a single center, randomized control. Sixty eligible subjects will be recruited into 3 study treatment groups (n=20 per group) through computerized randomization. Subjects in group 1 will be treated with 8% arginine containing paste(Colgate® Sensitive Pro-Relief™), group 2 with 5% topical fluoride varnish (Acclean) and group 3 with self-adhesive resin (Seal and protect, Dentsply). The subjects in the study will be evaluated for tactile and air-blast hypersensitivity criteria at baseline, two and four weeks.

Detailed description

The aim of the present study is to evaluate the efficacy of three common professionally applied desensitizing agents in the reduction of dentine hypersensitivity over a period of 4 weeks. Patients presenting to the dental clinic with Dentine hypersensitivity and fulfilling the inclusion criteria will be included in the study after taking informed consent. Participants will be divided into three groups. Sixty eligible subjects will be recruited into 3 study treatment groups (n=20 per group) through computerized randomization. Subjects in group 1 will be treated with 8% arginine containing paste(Colgate® Sensitive Pro-Relief™), group 2 with 5% topical fluoride varnish (Acclean) and group 3 with self-adhesive resin (Seal and protect, Dentsply). the subjects in the study will be evaluated for tactile and air-blast hypersensitivity criteria at baseline, two and at four weeks by another dentist who would be a blind assessor.

Conditions

• Dentine Hypersensitivity

Interventions

Type	Name	Description
DRUG	5% fluoride varnish	Applied topically as a coating at single point in time
DRUG	8% arginine containing paste	Applied topically as a coating at single point in time
DRUG	Self-adhesive resin	Applied topically as a coating at single point in time and light cured for 20 seconds

Timeline

• Start date: 2017-05-03
• Primary completion: 2018-12-20
• Completion: 2018-12-20
• First posted: 2017-06-06
• Last updated: 2018-06-29

Locations

1 site across 1 country: Pakistan