NCT03176810

Comparison Between Optimal Coherence Tomography Guidance and Angiography Guidance in Percutaneous Coronary Intervention

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 550 (actual)
• Sponsor: Takashi Kubo, MD · Academic / Other
• Sex: All
• Age: 20 Years – 100 Years
• Healthy volunteers: Not accepted

Summary

The present study aims to demonstrate the superiority of optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) compared with Angiography-guided PCI.

Detailed description

Comparison between Optimal Coherence tomography guidance and Angiography Guidance in percutaneous coronary intervention (COCOA) is a prospective, multicentre, randomised, open-label, parallel group, active-controlled, superiority trial comparing minimum stent area immediately after optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) with those after Angiography-guided PCI with a second generation drug-eluting stent.The primary endpoint of the present study was minimum stent area immediately after PCI. The secondary endpoint was target vessel failure (defined as a composite of cardiac death, target-vessel related myocardial infarction, and ischaemia-driven target vessel revascularisation).

Conditions

• Coronary Disease

Interventions

Type	Name	Description
DEVICE	OCT	OCT is used to guide PCI.
DEVICE	Angiography	Angiography is used to guide PCI.

Timeline

• Start date: 2017-04-01
• Primary completion: 2020-06-30
• Completion: 2021-06-30
• First posted: 2017-06-06
• Last updated: 2019-10-08

Locations

1 site across 1 country: Japan