NCT03176004

Attention Training to Modify Error-related Negativity and Risk for Anxiety in Adolescence

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 600 (actual)
• Sponsor: Florida State University · Academic / Other
• Sex: All
• Age: 11 Years – 14 Years
• Healthy volunteers: Accepted

Summary

This is a multi-site study to examine error-related brain activity (i.e., the error-related negativity) and anxiety symptoms in 11 to 14 year-olds (N=600) at two time points separated by two years. The study examines the degree to which error-related negativity can predict anxiety prospectively over two years, and whether a computerized game that alters attention to threat can alter error-related negativity and trajectories of anxiety.

Detailed description

Approximately 600 youths between the ages of 11 and 14 and their parents will be assessed. Adolescents will be evaluated at baseline using event-related potentials, self-report, and interview-based measures. The error-related negativity will be evaluated immediately (it takes less than 5 minutes to process and score a single subjects' error-related negativity ), and adolescents with good error-related negativity data (\~90%, based on scorable error-related negativity data) will be randomly assigned to either an 8-week (i.e., 16 session) adaptive attention bias modification (N=180) or control condition (N=180) or a waitlist condition (N=180) group. Each session lasts 20 minutes, and participants will be asked to complete two 20-minute sessions per week. Participants will be assessed immediately at post, using the same measures from the baseline assessment. All participants will complete a 2-year follow-up lab visit using the same measures from the baseline assessment.

Conditions

• Anxiety

Interventions

Type	Name	Description
OTHER	Attention Bias Modification	A computer game is used to facilitate attention away from threatening words.

Timeline

• Start date: 2016-10-01
• Primary completion: 2020-01-01
• Completion: 2021-12-01
• First posted: 2017-06-05
• Last updated: 2021-12-20

Locations

2 sites across 1 country: United States