NCT03174821

Effect Insulin Pump Therapy to Patients With Diabetic Nephropathy

The Impact of Insulin Pump Therapy to Oxidative Stress in Patients With Diabetic Nephropathy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 160 (actual)
• Sponsor: Chinese PLA General Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The recent study suggested that oxidative stress resulting from increased production of reactive oxygen species (ROS) plays a crucial role in the development of diabetic complications. The researches aim to monitor the level of oxidative stress of patient in different stage of diabetic nephropathy before and after insulin pump therapy.

Detailed description

Worldwidely, about 30% of Type 1 Diabetes Mellitus (T1DM) and 20%-50% of T2DM patients suffered diabetic nephropathy (DN). Oxidative stress resulting from increased production of reactive oxygen species (ROS) plays a crucial role in the development of diabetic complications. Insulin pump therapy is better than subcutaneous injection in terms of the drug safety and effectiveness. The researches aim to monitor the level of oxidative stress of patient in different stage of diabetic nephropathy before and after insulin pump therapy.

Conditions

• Insulin Pump Therapy in Treating Diabetic Nephropathy

Interventions

Type	Name	Description
DEVICE	Insulin pump	Blood glucose management device

Timeline

• Start date: 2010-10-20
• Primary completion: 2014-05-16
• Completion: 2014-05-16
• First posted: 2017-06-05
• Last updated: 2017-06-05