NCT03174743

Protective Ventilation During Pulmonary Lobectomy

The Effect of Protective Ventilation During Pulmonary Lobectomy

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 120 (estimated)
• Sponsor: Xuzhou Medical University · Academic / Other
• Sex: All
• Age: 20 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

The investigator will evaluate the influence of lung protective ventilation on postoperative clinical outcome in patients undergoing one-lung ventilation for pulmonary lobectomy.

Detailed description

The hypothesis is that application of low tidal volume, moderate inspired oxygen fraction (FiO2) ,intermittent alveolar recruitment and positive end-expiratory pressure (PEEP) would be more beneficial than conventional ventilation in patients.

Conditions

• Pulmonary Complication
• Thoracic Surgery
• Inflammation

Interventions

Type	Name	Description
PROCEDURE	Convential Ventilation 1	High tidal volume, moderate inspired oygen fraction (FiO2).
PROCEDURE	Convential Ventilation 2	High tidal volume, high inspired oygen fraction (FiO2).
PROCEDURE	Protective Ventilation 1	Low tidal volume, PEEP, moderate inspired oygen fraction (FiO2) and recruitment maneuver.
PROCEDURE	Protective Ventilation 2	Low tidal volume, PEEP, High inspired oygen fraction (FiO2) and recruitment maneuver.

Timeline

• Start date: 2017-06-02
• Primary completion: 2018-06-01
• Completion: 2018-07-01
• First posted: 2017-06-02
• Last updated: 2017-06-06

Locations

1 site across 1 country: China