NCT03174678

Dexmedetomidine Premedication in Children

The Effect of Oral Dexmedetomidine Premedication On Preoperative Cooperation and Emergence Delirium In Children Undergoing Dental Treatment

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 100 (actual)
• Sponsor: Aydin Adnan Menderes University · Academic / Other
• Sex: —
• Age: 2 Years – 6 Years
• Healthy volunteers: Accepted

Summary

The aim of this retrospective study was to detect the effectiveness of 1µg/kg oral dexmedetomidine premedication on preoperative cooperation and emergence delirium of the the young children underwent complete dental treatment.

Detailed description

One Hundred children between the ages 2-6 years of ASA I status underwent full mouth dental rehabilitation were enrolled in the study. Group Dex (n=50) received 1µg/kg dexmedetomidine in apple juice and Group control (n=50) received apple juice only. Patients' Ramsey Sedation Scale (RSS), The Parental Seperation Anxiety Scale (PSAS), Mask Acceptance Scale (MAS) and Post anesthesia emergence delirium scale (PAEDS) and hemodynamic parameters were noted from their patient file. Premedication period was 45 minutes and measurements of RSS and hemodynamic parameters were recorded in baseline and every 15 minutes until the patients were transferred to the operating room. The data were analysed using the Kruskal-Wallis test, two sample t- tests, chi-square tests and ANOVA.

Conditions

• Premedication

Interventions

Type	Name	Description
DRUG	Dexmedetomidine	1µg/kg dexmedetomidine oral
OTHER	apple juice	apple juice

Timeline

• Start date: 2017-03-01
• Primary completion: 2017-05-01
• Completion: 2017-05-25
• First posted: 2017-06-02
• Last updated: 2017-06-02

Locations

1 site across 1 country: Turkey (Türkiye)

Regulatory

• FDA-regulated drug study