NCT03174223

Influence of Deep Versus Moderate Neuromuscular Blockade During General Anesthesia on 30-day Readmission Rates

Influence of Deep Versus Moderate Neuromuscular Blockade During General Anesthesia on 30-day Readmission Rates: A Retrospective Analysis of Patient Chart Data

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 460 (actual)
• Sponsor: Leiden University Medical Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Deep neuromuscular block (NMB) has shown to produce superior surgical conditions during various abdominal and non abdominal surgeries. It is however unknown if the application of deep NMB leads to favourable outcome, such as lower rate of postoperative complications in general and surgical infections in specific and ultimately lower readmission rates. In the leiden university medical center, deep NMB is routinely applied for a variety of procedures, most notably laparoscopic abdominal and retroperitoneal surgery, eye surgery and neuro radiologic intervention surgery, since 2014. This retrospective study intends to investigate whether the application of deep NMB for these procedures affects patient outcome and readmission rates.

Conditions

• Postoperative Complications
• Postoperative Wound Infection
• Pneumonia

Interventions

Type	Name	Description
DRUG	deep neuromuscular block	a continuous dosing of rocuronium is used to achieve neuromuscular block of 1-2 twitches post tetanic count

Timeline

• Start date: 2017-06-01
• Primary completion: 2018-06-01
• Completion: 2018-07-01
• First posted: 2017-06-02
• Last updated: 2019-09-17

Locations

1 site across 1 country: Netherlands