Clinical Trials Directory

Trials / Terminated

TerminatedNCT03173430

Pilot Study of Blinatumomab in Combination With Salvage Autologous Stem Cell Transplantation for Patients With Refractory Multiple Myeloma

Status
Terminated
Phase
EARLY_Phase 1
Study type
Interventional
Enrollment
6 (actual)
Sponsor
Abramson Cancer Center at Penn Medicine · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

This study involves receiving blinatumomab after high-dose melphalan and ASCT for multiple myeloma. The main purpose of this study is to: - To determine whether blinatumomab is safe and feasible to administer after ASCT in patients with advanced multiple myeloma. - To assess how long multiple myeloma remains under control when blinatumomab is administered after second ASCT.

Conditions

Interventions

TypeNameDescription
DRUGBlinatumomabBlinatumomab (Blincyto), an anti-CD19/anti-CD3 bi-specific T cell engager

Timeline

Start date
2017-05-27
Primary completion
2019-01-28
Completion
2019-01-28
First posted
2017-06-01
Last updated
2020-02-07

Locations

1 site across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT03173430. Inclusion in this directory is not an endorsement.