NCT03173339

Influence of Remifentanil on Postoperative Sore Throat in Patients Undergoing General Anesthesia

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 92 (actual)
• Sponsor: Keimyung University Dongsan Medical Center · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

This investigation is planned to compare the incidence and severity of postoperative sore throat according to the dose of remifentanil.

Conditions

• Hip Arthroplasty

Interventions

Type	Name	Description
PROCEDURE	Endotracheal intubation using laryngoscope	Endotracheal intubation was done using laryngoscope for general anesthesia.
DRUG	High remifentanil	Remifentanil was started as 0.25 mcg/kg/min. Remifentanil dose was adjusted to maintain blood pressure (20% of preoperative blood pressure) and bispectral index (40-60) by 0.05 mcg/kg/min.
DRUG	Low remifentanil	Remifentanil was administered as 0.1 mcg/kg/min.
DRUG	High sevoflurane	Sevoflurane was started as 0.5 MAC. Sevoflurane dose was adjusted to maintain blood pressure (20% of preoperative blood pressure) and bispectral index (40-60) by 0.2 %.
DRUG	Low sevoflurane	Sevoflurane was administered as 0.5 MAC.

Timeline

• Start date: 2017-06-01
• Primary completion: 2017-08-24
• Completion: 2017-08-24
• First posted: 2017-06-01
• Last updated: 2017-08-25

Locations

1 site across 1 country: South Korea