NCT03172663

Body Mass Index and Audiology Function

Effect of Increased Body Mass Index on Auditory Function

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: 10 Years – 40 Years
• Healthy volunteers: Accepted

Summary

Obesity may directly or indirectly lead to hearing loss

Detailed description

Obesity is measured by Body Mass Index.it is calculated by dividing a person's weight in kilograms by the square of height in meters. For children and adolescent. Overweight is defined as Body Mass Index is \<85th percentile \<95th percentile but obesity is defined as body mass index at or above the 95th percentile for children and teens of the same age and sex the increasing in body mass index mass may affect auditory function Directly as adipose tissue secretes hormones and cytokines, proinflammatory cytokines lead to release of obesity-induced inflammation which may directly contribute to end-organ damage Also, Adiponectin, which is thought to have anti-inflammatory and antiatherogenic effects, and associated with favorable lipoprotein profile, independent of BMI and insulin resistance, low plasma concentrations of adiponectin have been associated with obesity in children. In adults, low level of adiponectin has been associated with elevated high-frequency thresholds. Indirectly, by obesity comorbidities including Hypertension, Type 2 diabetes mellitus, Dyslipidemia , Metabolic Syndrome and Cardiovascular Diseases

Conditions

• Hearing Loss

Interventions

Type	Name	Description
DEVICE	pure tone audiometry	for estimate the type and degree of hearing loss

Timeline

• Start date: 2018-05-01
• Primary completion: 2019-05-01
• Completion: 2019-11-01
• First posted: 2017-06-01
• Last updated: 2017-06-06