NCT03171129

ADINA vs. High Flow Nasal Cannula Comparison Study

Adaptive Dynamic Inspiratory Nasal Apparatus (ADINA): Comparison to High Flow Nasal Cannula (HFNC)

• Status: Not Yet Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (estimated)
• Sponsor: Loma Linda University · Academic / Other
• Sex: All
• Age: 23 Weeks – 40 Weeks
• Healthy volunteers: Not accepted

Summary

This study is to evaluate the feasibility of using a pressure limited nasal cannula system instead of a high flow nasal cannula system in the management of premature babies with respiratory distress.

Detailed description

NCPAP has been used increasingly to manage respiratory distress in newborns as well as apnea of prematurity. Humidified high flow nasal cannula devices (flows 1-8 lpm) have also been used in neonatal intensive care units. This study is to evaluate the feasibility of using a pressure limited nasal cannula system instead of a high flow nasal cannula system in the management of premature babies with respiratory distress.

Conditions

• Respiratory Distress Neonatal

Interventions

Type	Name	Description
DEVICE	Adaptive Dynamic Inspiratory Nasal Apparatus	Oxygen will be administered via ADINA
DEVICE	High flow Nasal Canula	Oxygen will be administered via nasal canula

Timeline

• Start date: 2026-07-01
• Primary completion: 2027-09-01
• Completion: 2027-09-01
• First posted: 2017-05-31
• Last updated: 2026-01-30

Locations

1 site across 1 country: United States

Regulatory

• FDA-regulated device study