NCT03169595

Epithelioid Hemangioma of Bone And Soft Tissue

Epithelioid Hemangioma of Bone And Soft Tissue: a Benign Tumor With Metastatic Potential

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 70 (actual)
• Sponsor: Istituto Ortopedico Rizzoli · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

The controversy surrounding epithelioid hemangioma diagnosis stems from its somewhat aggressive clinical characteristics, including multifocal presentation and occasional lymph node involvement. The investigators reviewed the clinicopathologic and radiologic characteristics of bone and soft tissue epithelioid hemangioma in patients treated at our institution with available tissue for molecular testing. The hypothesis is that epithelioid hemangioma may present with multifocal involvement and rare loco-regional lymph node metastasis, but it remains a benign tumor with excellent prognosis.

Detailed description

The investigators retrospectively reviewed patients treated for epithelioid hemangioma of the bone and soft tissue in a single insitution. The purpose of this study is to evaluate the pathological, clinical, and radiological characteristics of epithelioid hemangioma arising within bone and soft tissue, in the first cohort of cases where the definitive diagnosis is supplemented by molecular techniques. The hypothesis is that the improved knowledge regarding this rare entity can more definitively elucidate the benign biology of epithelioid hemangioma.

Conditions

• Epithelioid Hemangioma of Bone
• Epithelioid Hemangioma

Interventions

Type	Name	Description
PROCEDURE	Surgery	Patients affected by epithelioid hemangioma treated with surgery

Timeline

• Start date: 2015-10-07
• Primary completion: 2017-05-17
• Completion: 2017-05-17
• First posted: 2017-05-30
• Last updated: 2017-05-30