Trials / Terminated
TerminatedNCT03169530
Moderate Alcohol and Cardiovascular Health Trial
- Status
- Terminated
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 103 (actual)
- Sponsor
- Beth Israel Deaconess Medical Center · Academic / Other
- Sex
- All
- Age
- 50 Years
- Healthy volunteers
- Not accepted
Summary
The Moderate Alcohol and Cardiovascular Health Trial (MACH15) is a multicenter, worldwide, randomized clinical trial of \~15 gm of alcohol daily versus abstention, using a balanced parallel design and single-blind assessment of all outcomes among approximately 7,800 participants aged 50 years and older with advanced cardiovascular risk. Intervention will average 6 years in duration with a common close-out date. Following recruitment and pre-screening, participants will attend a screening visit followed by a two-week abstention washout period, a baseline visit and randomization, and subsequent visits at 3 months, 6 months, 12 months, and then annually until close-out.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Alcohol | \~15 gm daily of beer, wine, or spirits for \~6 years |
Timeline
- Start date
- 2018-02-05
- Primary completion
- 2018-06-15
- Completion
- 2018-06-15
- First posted
- 2017-05-30
- Last updated
- 2019-03-15
- Results posted
- 2019-01-30
Locations
4 sites across 3 countries: United States, Netherlands, Nigeria
Source: ClinicalTrials.gov record NCT03169530. Inclusion in this directory is not an endorsement.