NCT03169348

The Effect of Direct Antiviral Therapy on Hepatitis c Virus-related Thrombocytopenia

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 50 (estimated)
• Sponsor: Assiut University · Academic / Other
• Sex: All
• Age: —
• Healthy volunteers: Not accepted

Summary

Autoimmune thrombocytopenic purpura is an immunological disorder characterized by increased platelet destruction due to presence of anti-platelet antibodies. Hepatitis C virus infection, which is one of the most common chronic viral infections worldwide, may cause secondary chronic immune thrombocytopenic purpura. It seemed to play a pathogenic role in autoimmune thrombocytopenic purpura. Moreover, the successful response (negative hepatitis C virus - ribonucleic acid) to tapered steroids and antiviral therapy was useful to revert thrombocytopenia

Conditions

• Hepatitis C

Interventions

Type	Name	Description
DRUG	sofosbuvir daclatasvir	oral tablets
DRUG	Ledipasvir/sofosbuvir	oral tablets

Timeline

• Start date: 2017-11-01
• Primary completion: 2019-06-01
• Completion: 2019-09-01
• First posted: 2017-05-30
• Last updated: 2017-12-07

Locations

1 site across 1 country: Egypt