NCT03168152

Randomized Trial Comparing Stereotactic Body Radiation Therapy to Microwave Ablation for the Treatment of Localized Hepatocellular Carcinoma

A Phase II Randomized Trial Comparing Stereotactic Body Radiation Therapy to Microwave Ablation for the Treatment of Localized Hepatocellular Carcinoma

• Status: Withdrawn
• Phase: N/A
• Study type: Interventional
• Enrollment: 0 (actual)
• Sponsor: University of Michigan Rogel Cancer Center · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This is a randomized phase II study comparing microwave ablation (MWA) and stereotactic body radiation therapy (SBRT) for localized hepatocellular carcinoma (HCC). This trial will be the first prospective comparison of these modalities for the treatment of HCC and will provide critical information regarding which local ablative modality is most appropriate for which patients. This study will also provide important information regarding quality of life and liver function changes following these two different treatment modalities.

Conditions

• Carcinoma, Hepatocellular

Interventions

Type	Name	Description
RADIATION	Microwave Ablation (MWA)	MWA will typically be administered in one ablation session during which time up to 2 tumors are treated.
RADIATION	Stereotactic Body Radiation Therapy (SBRT)	SBRT will be administered in five fractions of up to 10 Gy per fraction. SBRT will be administered 5-15 days per tumor.

Timeline

• Start date: 2017-05-11
• Primary completion: 2022-04-01
• Completion: 2022-04-01
• First posted: 2017-05-30
• Last updated: 2018-06-25

Locations

1 site across 1 country: United States