NCT03168087

Plasmalyte-148 Solution and Blood Coagulation

The Effect of a Plasmalyte-148 Solution on Blood Coagulation: In Vitro, Volunteer Study Using Rotational Thromboelastometry

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 12 (actual)
• Sponsor: Seoul National University Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Fluids administered intravenously may alter whole blood coagulation. However, little is known about the dose-response relationships of hemodilution in plasmalyte-148 solution. Investigators have therefore performed the present study to measure the effect of a plasmalyte-148 solution on the coagulation pathway according to the hemodilution level using a rotational thromboelastometry (ROTEM®) tests.

Conditions

• Blood Coagulation Disorder

Interventions

Type	Name	Description
OTHER	Plasmalyte-148	Venous blood is taken from 12 healthy volunteers and divided into four specimen bottles, which were diluted with different levels (0%, 20%, 40%, and 60%) using a plasmalyte-148 solution.

Timeline

• Start date: 2017-05-15
• Primary completion: 2018-08-23
• Completion: 2018-08-30
• First posted: 2017-05-30
• Last updated: 2020-02-13

Locations

1 site across 1 country: South Korea