Trials / Completed
CompletedNCT03168009
Brown Fat Activity and Bariatric Surgery
The Role of Alternatively Activated Brown Fat in Bariatric Surgery-mediated Metabolic Improvements
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (actual)
- Sponsor
- Medical University of Vienna · Academic / Other
- Sex
- All
- Age
- 20 Years – 50 Years
- Healthy volunteers
- Not accepted
Summary
The mechanisms of bariatric surgery-induced weight loss go beyond reductions in calorie intake and may involve several other pathways. Recently, brown adipose tissue (BAT) has been added as another potential player. Activation of BAT results in enhanced energy expenditure and promotes weight loss. Here, the investigators will study the effects of bariatric surgery on BAT function by PET/CT studies and molecular analyses of adipose biopsies. The investigators will explore different pathways that may affect BAT activation in this patient population.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Bariatric Surgery | Patients will undergo bariatric surgery as routinely scheduled. The type of bariatric procedure will be suggested by the surgeon based on clinical considerations. |
Timeline
- Start date
- 2017-05-24
- Primary completion
- 2021-12-31
- Completion
- 2021-12-31
- First posted
- 2017-05-30
- Last updated
- 2022-04-12
Locations
1 site across 1 country: Austria
Source: ClinicalTrials.gov record NCT03168009. Inclusion in this directory is not an endorsement.