NCT03167762

Photographing the Skin During Photodynamic Therapy

Fluorescence and Thermal Imaging of the Skin Before and During Photodynamic Therapy

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 18 (actual)
• Sponsor: University of Dundee · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Photodynamic therapy (PDT) is used to treat some types of sun-damaged skin and low-grade forms of growths. A cream is applied to the skin, and the chemical in this cream is absorbed in to the skin and converted in to a 'photosensitiser'. This photosensitiser is fluorescent, meaning that it produces red light when blue light is shone on it. By measuring how much light is given off with a camera, the investigators can determine how much photosensitiser is present in the skin. Also, it is thought that more of the chemical is converted to the active photosensitiser if the skin is warmer, so the investigators plan to measure the temperature of the skin using a thermal camera. Light is shone on to the skin and this activates the photosensitiser, treating the problem area and leaving healthy skin intact. This research will increase the investigators understanding of how PDT works, and may help the investigators to improve treatment regimens so that they can be made more effective and better tolerated

Conditions

• Basal Cell Carcinoma
• Bowen's Disease

Interventions

Type	Name	Description
DEVICE	Fluorescence and thermal imaging	Two cameras used to take images of the skin. One, to measure the fluorescence from the photosensitiser, and the second to measure the surface temperature of the skin

Timeline

• Start date: 2017-06-22
• Primary completion: 2020-06-22
• Completion: 2021-06-01
• First posted: 2017-05-30
• Last updated: 2021-07-16

Locations

1 site across 1 country: United Kingdom