NCT03164590

Effects of Wound Infiltration With Ketamine Versus Dexmedetomidine Added to Bupivacaine on Cytokines

Effects of Local Wound Infiltration With Ketamine Versus Dexmedetomidine Added to Bupivacaine on Inflammatory Cytokines Response After Total Abdominal Hysterectomy

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 60 (actual)
• Sponsor: Assiut University · Academic / Other
• Sex: Female
• Age: 18 Years – 60 Years
• Healthy volunteers: Not accepted

Summary

This study aims to compare the effects of local wound infiltration with ketamine versus dexmedetomidine when added to bupivacaine on inflammatory cytokine response after total abdominal hysterectomy.

Conditions

• Endometrial Adenocarcinoma

Interventions

Type	Name	Description
DRUG	Ketamine	patients receive local anesthetic wound infiltration with 1 mg /kg ketamine
DRUG	dexmedetomidine	patients receive local anesthetic wound infiltration with 1µg/kg dexmedetomidine
DRUG	bupivacaine	patients receive local anesthetic wound infiltration with bupivacaine 0.5 % diluted in 20 ml saline

Timeline

• Start date: 2017-06-01
• Primary completion: 2018-08-01
• Completion: 2018-09-01
• First posted: 2017-05-23
• Last updated: 2020-01-22

Locations

1 site across 1 country: Egypt

Regulatory

• FDA-regulated drug study