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UnknownNCT03164096

The Effect of Some Parturients' Characteristics on Sensory Block Level After Spinal Anesthesia

The Effect of Body Mass Index, Intra-abdominal Pressure, Abdominal Girth and Waist Circumference on Sensory Block Level After Single-shot Spinal Anesthesia for Cesarean Section

Status
Unknown
Phase
Phase 4
Study type
Interventional
Enrollment
100 (estimated)
Sponsor
Assiut University · Academic / Other
Sex
Female
Age
18 Years – 40 Years
Healthy volunteers
Not accepted

Summary

Although the exact mechanism remains unknown, the association of pregnancy and decreased local anesthetic requirement is clear. demonstrated that more local anesthetic is required for cesarean section under combined spinal-epidural anesthesia in preterm compared with term patients.

Detailed description

However, in pregnant patients, venous engorgement is prominent in the supine but not the lateral position, which suggests direct compression of the inferior vena cava by the gravid uterus. Second, an increase in intraabdominal pressure may affect the retroperitoneal area and may cause inward movement of soft tissue in the intervertebral foramina. Recent magnetic resonance imaging studies in pregnant patients, although without intraabdominal pressure measurements, suggested the latter because they showed limited contact of engorged veins along the dural sac which may therefore not be responsible for compression of the dura. If elevated intraabdominal pressure contributes to high anesthetic spread during pregnancy, one would expect a relationship between intraabdominal pressure and maximum sensory block level.

Conditions

Interventions

TypeNameDescription
DRUGBupivacaine Hydrochlorideintrathecal bupivacaine will be used for spinal anesthesia in obstetric patients undergoing C-section

Timeline

Start date
2017-06-01
Primary completion
2018-12-01
Completion
2018-12-10
First posted
2017-05-23
Last updated
2018-03-29

Locations

1 site across 1 country: Egypt

Source: ClinicalTrials.gov record NCT03164096. Inclusion in this directory is not an endorsement.

The Effect of Some Parturients' Characteristics on Sensory Block Level After Spinal Anesthesia (NCT03164096) · Clinical Trials Directory