Clinical Trials Directory

Trials / Unknown

UnknownNCT03163329

The Safety and Effectiveness of Transcatheter Aortic Valve Raplacemet in Intermediate Risk Patients With Bicuspid Aortic Stenosis

A Prospective, Randomized, Controlled, Multi-Center Study to Establish the Safety and Effectiveness of Transcatheter Aortic Valve Raplacemet in Intermediate Risk Patients Who Have Severe, Calcific, Bicuspid, Aortic Stenosis Requiring Aortic Valve Replacement

Status
Unknown
Phase
Phase 2
Study type
Interventional
Enrollment
300 (estimated)
Sponsor
China National Center for Cardiovascular Diseases · Other Government
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Previous trials have shown that TAVR was a noninferior alternative to surgery in patients with severe aortic stenosis at intermediate surgical risk. However, patients with congenital bicuspid valve have been excluded in those trials. The purpose of this trial is to determine the safety and effectiveness of TAVR in intermediate-risk patients with bicuspid aortic valve stenosis.

Conditions

Interventions

TypeNameDescription
PROCEDURETAVRTranscatheter Aortic Valve Replacement
PROCEDURESAVRSurgical Aortic Valve Replacement

Timeline

Start date
2018-02-01
Primary completion
2020-10-31
Completion
2024-10-31
First posted
2017-05-23
Last updated
2018-01-11

Source: ClinicalTrials.gov record NCT03163329. Inclusion in this directory is not an endorsement.